What is the immune checkpoint for immune cells?
In general, foreign substances entering the immune system triggers an inflammatory reaction, and also triggers immune cells to activate and fight against foreign substances. However, excessive activation of the immune system, while effective in killing these foreign substances, can cause damage to the body’s healthy cells. This is why an inhibition mechanism is required, so that there is no stimulation past a certain point. The main function of this checkpoint is to help suppress the immune system, control its reaction to a certain extent and to help it halt external invasions while keeping the body healthy.
